Title: PROTEIN STRUCTURE PREDICTION. A PRACTICAL APPROACH. (PRACTICAL APPROACH SERIES)
Publisher: Oxford University Press
Publication Date: 1997
Language: English
ISBN 10: 0199634971
ISBN 13: 9780199634972
Binding: Hardcover
Condition: New
Dust Jacket Condition: No Jacket

About this title

Synopsis

The prediction of the three-dimensional structure of a protein from its amino acid sequence is a problem faced by an increasing number of biological scientists. This book provides a practical guide to making these predictions by reviewing strategies of different computer modeling algorithms and highlighting the degree of confidence attributed to them. Also in the volume are descriptions of the following: the principles of protein folding; sequence homology and motif searches; prediction of secondary structure; homology modeling; modeling of antibody combining sites; tertiary fold recognition; modeling of transmembrane proteins; ab initio prediction; protein-ligand docking simulations; and the use of molecular mechanics and dynamics. both non-specialists who require guidance to identify and evaluate appropriate strategies and experts who require a contemporary view of the field, will find this volume a worthy addition to their research libraries.

About the Author

M. Sternberg, Head of Laboratory, Laboratory of Biomolecular Modelling, Imperial Cancer Research Fund, London.

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