Parallel Single Cell Electrophoresis in a Microchip Platform

Munce, Nigel, Lilge, Lothar

ISBN 10: 3838304489 / ISBN 13: 9783838304489

Published by LAP LAMBERT Academic Publishing, 2010

About this Item

NEW. SHIPS FROM MULTIPLE LOCATIONS.

Seller Inventory # ERICA82938383044896

Bibliographic Details

• Title: Parallel Single Cell Electrophoresis in a Microchip Platform
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2010
• Language: English
• ISBN 10: 3838304489
• ISBN 13: 9783838304489
• Binding: paperback
• Condition: New
• Book Type: book

About this title

Synopsis

Single cell analysis has typically been difficult and challenging to perform in such a way that meaningful statistical information can be extracted. This thesis documents the development of a microchip or lab-on-a-chip platform to perform single cell electrophoresis in parallel separation channels. It describes the use of optical tweezers to select a cell and transport it to a desired separation channel. It also describes the use of electromechanical shearing to lyse a cell. These two techniques are combined with laser-micromachined separation channels to perform simple electrohoresis on the fluorescently labeled cellular contents.

About the Author

Nigel Munce is currently a research scientist and medical student at the University of Toronto in Canada. He is interested in both medical devices and the development of new medical imaging techniques.