This book addresses the challenges in the differential diagnosis and management of paroxysmal movement disorders. It provides the latest information on the genetics and pathophysiology, neurophysiology and neuroimaging of the core group of disorders in the field, namely the paroxysmal dyskinesias (PxD).

Focused and concise, this guide features chapters that discuss other conditions that may be paroxysmal such as, episodic ataxia, startle syndromes and other more complicated groups of paroxysmal movement disorders such as ATP1A3 spectrum disorders. A chapter on secondary (acquired) paroxysmal dyskinesia highlights medical and other disorders that may result in paroxysmal dyskinesia. The book features a particularly nuanced chapter that discusses recent discoveries in the genetic aspects of PxD, relaying that paroxysmal dyskinesias are not channelpathies, but in fact are synaptophies and transportopathies. Additionally, expertly written chapters are supplemented by high qualityimages, tables, and videos.

Paroxysmal Movement Disorders: A Practical Guide is primarily written to educate the reader on how to make a syndromic diagnosis of paroxysmal movement disorders and how to build the diagnostic work-up accordingly, as well as how to manage patients with paroxysmal movement disorders.

About the Author

Kapil D. Sethi, MD, FRCP, FAAN

Department of Neurology

Movement Disorders Section

Augusta University

Augusta, GA

USA

Roberto Erro, MD, PhD

Center for Neurodegenerative Diseases (CEMAND)

Department of Medicine

Surgery and Dentistry “Scuola Medica Salernitana”

University of Salerno

Baronissi (SA)

Italy

Kailash P. Bhatia, MD, DM, FRCP

Department of Clinical and Movement Neurosciences,

UCL Queen Square Institute of Neurology

National Hospital for Neurology and Neurosurgery

London

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