Patch-Clamp Methods and Protocols

. Ed(s): Molnar, Peter; Hickman, James J.

ISBN 10: 1617377244 / ISBN 13: 9781617377242

Published by Humana Press Inc., 2010

About this Item

Editor(s): Molnar, Peter; Hickman, James J. Series: Methods in Molecular Biology. Num Pages: 332 pages, 71 black & white illustrations, 4 black & white tables, biography. BIC Classification: MFG; MMG; PHVN; PSAN. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 19. Weight in Grams: 498. . 2010. 1st ed. Softcover of orig. ed. 2007. Paperback. . . . . Books ship from the US and Ireland.

Seller Inventory # V9781617377242

Bibliographic Details

• Title: Patch-Clamp Methods and Protocols
• Publisher: Humana Press Inc.
• Publication Date: 2010
• Language: English
• ISBN 10: 1617377244
• ISBN 13: 9781617377242
• Binding: Soft cover
• Condition: New

About this title

Synopsis

Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described require a basic level of electrophysiological training, and aid the researcher in pursuing new areas of electrophysiology and using the patch clamp technique effectively. Patch Clamp Methods and Protocols is organized by the major areas of patch clamp application: Pharmacology, Physiology, and Biophysics. Individual techniques are explored within the area that they are applied most often. Researchers will find this text to be an invaluable aid in the design and execution of a wide variety of patch clamp experiments, both on their own and in conjunction with other state-of-the-art methodologies.

From the Back Cover

Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described require a basic level of electrophysiological training and aid the researcher in pursuing new areas of electrophysiology and using the patch clamp technique effectively. Patch Clamp Methods and Protocols is divided into three sections that cover the major areas of patch clamp application: Pharmacology, Physiology, and Biophysics. The first section provides examples and step by step instructions on how to use whole-cell and single-channel patch clamp methods for testing drugs in industrial settings. The second section provides a wide selection of patch clamp applications in physiological studies. The last part focuses on the biophysical applications of the patch clamp method using single channel recordings or statistical analysis of whole-cell currents in order to obtain parameters that describe ion channel properties or transmitter release. Individual techniques are explored within the area that they are applied most often. Researchers will find Patch Clamp Methods and Protocols to be an invaluable aid in the design and execution of a wide variety of patch clamp experiments, both on their own and in conjunction with other state-of-the-art methodologies.