Patch-Clamp Methods and Protocols

Language: English

Published by Humana Jul 2014, 2014

1493910957 / 9781493910953

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This item is printed on demand - Print on Demand Titel. Neuware -Since its inception, patch-clamp has continued to be widely considered the gold standard method to record ion channel activity. Patch-Clamp Methods and Protocols, Second Edition, provides a comprehensive collection of new techniques for the development of automated, high-throughput screening systems for pharmacological evaluation, the use of various patch-clamp configurations together with novel molecular biological and imaging methodologies and enhanced stimulation protocols and perfusion systems. Divided into sections on pharmacology, physiology and biophysics, the chapters cover methods to generate more physiologically relevant conditions for drug application and screening technologies, recently developed applications such as optogenetic stimulation, advances in whole-cell recordings in freely-moving animals and novel technologies to create custom microelectrodes designed for reducing the access resistance and improving the rate of molecular diffusion. Patch-clamp is an indispensable technique for conducting pharmacological, physiological and biophysical research aimed at understanding crucial aspects of cellular and network function. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Patch-Clamp Methods and Protocols, Second Edition will provide a useful technical and methodological guide to diverse audiences of electrophysiologists, from students to experienced investigators.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 416 pp. Englisch.…

Seller Inventory # 9781493910953

Title
Patch-Clamp Methods and Protocols
Author
Marzia Martina
Publisher
Humana Jul 2014
Publication year
2014
Condition
Neu
Binding
Buch
Language
English
ISBN 10
1493910957
ISBN 13
9781493910953
Edition
2nd Edition
Item weight
976 grams
Dimensions
260x183x28 mm

buchversandmimpf2000

Emtmannsberg, BAYE, Germany

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