Die Patch-Clamp-Technik ist heute eine der wichtigsten neurophysiologischen Arbeitsmethoden. Ihre Anwendung hat in der biomedizinischen Grundlagenforschung bedeutende Erkenntnisse �ber die Funktion und die Eigenschaften von Ionenkan�len erbracht, und auch aus der angewandten pharmakologischen Forschung ist sie in�zwischen nicht mehr wegzudenken. Klar und praxisbezogen vermitteln die Autoren die wesentlichen Informationen, um die Methode im Labor einzuf�hren und erfolgreich anzuwenden. Das Buch erl�utert die theoretischen Grundlagen der Messung, den detaillierten Aufbau eines Messplatzes und die praktische Durchf�hrung typischer Messkonfigurationen. Konkrete Tipps und Tricks helfen beim „Trouble-Shooting“ und sind nicht nur f�r Neuanwender eine unverzichtbare Hilfe.

About the Author

Fabian Roth ist Neurobiologe und forscht und lehrt am Institut f�r medizinische Grundlagenforschung (IMB) der Universit�t Oslo.

Markus Numberger ist Biologe und arbeitet freiberuflich als Wissenschaftsautor in den Bereichen Medizin, Pharmazie und Biologie.

Andreas Draguhn ist Mediziner und Hochschullehrer am Universit�tsklinikum Heidelberg der Ruprecht-Karls-Universit�t Heidelberg.

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