Pharmaceutical Drug Analysis by Atomic Absorption Spectroscopy | Basics, Concepts, & Methods

Sunil Jawla

ISBN 10: 3659409057 / ISBN 13: 9783659409059

Published by LAP LAMBERT Academic Publishing, 2013

About this Item

Pharmaceutical Drug Analysis by Atomic Absorption Spectroscopy | Basics, Concepts, & Methods | Sunil Jawla | Taschenbuch | 96 S. | Englisch | 2013 | LAP LAMBERT Academic Publishing | EAN 9783659409059 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

Seller Inventory # 105887881

Bibliographic Details

• Title: Pharmaceutical Drug Analysis by Atomic Absorption Spectroscopy | Basics, Concepts, & Methods
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2013
• Language: English
• ISBN 10: 3659409057
• ISBN 13: 9783659409059
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 6D millimeters 220 millimeters width by 150 millimeters height by 6 millimeters depth
• Weight: 161 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

Naproxen and ibuprofen (aryl propionic acid derivatives) both are classified as non-steroidal anti-inflammatory agents. Except HPLC, no sensitive methods were reported for both the drugs. HPLC methods suffer from two drawbacks- first; requirement of costly chemicals and second; more time consuming. Because atomic absorption spectroscopy (AAS) methods are simple, sensitive, rapid, reproducible and uses low cost chemicals. The objective of present research work was to develop highly sensitive and economical analytical methods for the quantitative estimation of naproxen and ibuprofen in pharmaceutical formulations by AAS. The methods were based on the reaction of naproxen and ibuprofen with copper and cobalt chloride to form coloured metal complexes. These complexes were extracted with organic solvents and digested with acids. Naproxen and ibuprofen were indirectly estimated by AAS via the determination of the copper and cobalt content in the formed complexes. The proposed methods may be used for routine analysis of pharmaceutical formulations containing aryl propionic acid derivatives and similar pharmaceutical drugs by the analytical chemist.

About the Author

Mr. Sunil Jawla (M. Pharm, GATE) is currently working as Assistant Professor (Pharmaceutical Chemistry) at ITS Paramedical College (Pharmacy), Ghaziabad, India. He has more than 9 years of teaching and research experience. His research interests are isolation of antidiabetic leads from naturals, molecular modelling & analytical method developments.