The Placenta and Human Developmental Programming

ISBN 10: 052119945X ISBN 13: 9780521199452
Published by Cambridge University Press, 2011
Used Hardcover

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Synopsis:

Developmental programming is a rapidly advancing discipline of great importance to basic scientists and health professionals alike. This text integrates, for the first time, contributions from world experts to explore the role of the placenta in developmental programming. The book considers the materno-fetal supply line, and how perturbations of placental development impact on its functional capacity. Chapters examine ways in which environmental, immunological and vascular insults regulate expression of conventional and imprinted genes, along with their impact on placental shape and size, transport, metabolism and endocrine function. Research in animal models is integrated with human clinical and epidemiological data, and questions for future research are identified. Transcripts of discussions between the authors allow readers to engage with controversial issues. Essential reading for researchers in placental biology and developmental programming, as well as specialists and trainees in the wider field of reproductive medicine.

About the Authors: Graham J. Burton is Professor of Reproductive Biology and Director of the Centre for Trophoblast Research, University of Cambridge, Cambridge, UK.

David J. P. Barker is Director of the MRC Epidemiology Resource Centre (University of Southampton), Southampton General Hospital, UK.

Ashley Moffett is Professor of Reproductive Immunology at the University of Cambridge and Director of Studies in Medicine at King's College, Cambridge, UK.

Kent Thornburg is Director of the Heart Research Center and Professor of Cardiovascular Medicine, University of Oregon, Portland, USA.

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Bibliographic Details

Title: The Placenta and Human Developmental ...
Publisher: Cambridge University Press
Publication Date: 2011
Binding: Hardcover
Condition: As New
Dust Jacket Condition: No Jacket

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