Plaque Imaging: Pixel to Molecular Level (= Studies In Health Technology And Informatics, Vol. 113). This item is unavailable.Plaque Imaging: Pixel to Molecular Level (= Studies In Health Technology And Informatics, Vol. 113)

This publication starts of with a review of plaque imaging techniques, with an introduction of the segmentation techniques for plaque classification and quantification. Many aspects of plaque imaging techniques are presented in this publication, such as; medical image retrieval and database management, MRI techniques to differentiate stable versus high risk atherosclerosis, composition and morphology of atherosclerotic plaque, analysis of the soft tissue based on computer vision techniques, modelling of coronary artery biomechanics, Cardiac CT for the assessment of cardiovascular pathology with an emphasis on the detection of coronary atherosclerosis, technical and practical issues regarding coronary atherosclerotic plaque imaging by CT (focussing on coronary calcium imaging), feasibility of a non-invasive, in vivo determination of the IBS of arterial wall tissue, high resolution ultrasound images of carotid plaques, the problem of reliable features extraction and classification process and a discussion on advanced mathematical techniques to extract spectral information from the RF data to determine the plaque composition.

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Coronary disease is the number one cause of death in the United States and the Western world and approximately 250,000 affected people die per year without being admitted to the hospital. One of the main reasons of such a high death rate without any diagnostics in more than 50% of myocardial infarctions (Mis or heart attacks) occur in patients with no prior history of heart attack disease or symptoms. Coronary artery disease leads to the occlusion of arteries that are vital in providing nutrients to the heart muscles. The disease develops by progressive accumulation or formation of 'plaque' within an artery. Certain types of arteries could occlude blood flow and yet might be 'stable'. These plaques usually have high fibrous content and are known as hard plaques. On the other hand, 'unstable or soft plaques' might not cause much occlusion but could be venerable to rupture. Rupture of such plaques could lead to total or partial occlusion in arteries resulting in sudden cardiac death or heart attack. In fact, 68% of the MIs are caused by rupture of plaques when coronary arteries are less than 50% occluded. This book is about plaque imaging covering both clinical and imaging aspects of plaque using Magnetic Resonance (MR), Computer Tomography (CT), Intravascular Ultrasound (IVUS), Elastography and at Molecular/Microscopic levels.