Plasma Elemental Concentrations, Auditory Pathway Disorder, and Auditory Deficits in OSMF

Auriga

ISBN 13: 9798231550487

Published by Independent Publisher, 2025

About this Item

Plasma Elemental Concentrations, Auditory Pathway Disorder, and Auditory Deficits in OSMF | Auriga | Taschenbuch | Englisch | 2025 | Independent Publisher | EAN 9798231550487 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.

Seller Inventory # 133459005

Bibliographic Details

• Title: Plasma Elemental Concentrations, Auditory Pathway Disorder, and Auditory Deficits in OSMF
• Publisher: Independent Publisher
• Publication Date: 2025
• Language: English
• ISBN 13: 9798231550487
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 280W x 216H x 6D millimeters 280 millimeters width by 216 millimeters height by 6 millimeters depth
• Weight: 276 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

The pathogenesis of OSMF has multifactorial etiology including nutritional deficiencies, ingestion of chillies, habit of chewing areca nut, factors like pollution and genetic and immunologic processes.

1. Chewing of Areca nut (betel nut):

The major component of betel quid is areca nut, tobacco, lime and piper leaf. Betel nut is a major etiologic agent in OSMF. Betel nut consists of arecoline, an active alkaloid which stimulates fibroblast to increase production of collagen by 150%and also upregulates COX-2 expression. It causes increased collagen production leading to fibrosis. Areca nut quid contains cytotoxic & genotoxic agents which leads to arecoline cytotoxicity and stimulates self-proliferation and thiol- depletion . Earlier studies have reported that, OSMF remains active even after termination of the chewing habit signifying that components of areca nut initiate OSMF. Gene expression in the fibroblasts is affected by areca nut, due to which greater amount of normal collagen is produced in OSMF.. Trivedy C et al. conducted a study and concluded that there is increased level of copper in saliva after placing a areca nut quid in mouth for 5- 10 min. Copper stimulates fibrogenesis through up -regulation of lysyl oxidase activity by working as an initiating factor in OSMF .