Polymer Nanoparticles for Nanomedicines: A Guide for their Design, Preparation and Development

This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.

Christine Vauthier is Director of Research at the CNRS (Centre National de la Recherche Scientifique) at the Institut Galien Paris Sud, Université Paris-Sud, France. Dr. Vauthier also serves as an editor for the journal Pharmaceutical Research. She received her Ph. D. in polymer chemistry from the University Louis Pasteur at Strasbourg, France.  She then joined the University of Paris South, Faculty of Pharmacy as a research assistant. The focus of her research is about understanding the influence of the physicochemical characteristics of nanomedicines and their interactions with biological systems when the nanomedicines are intended to improve drug delivery after mucosal or intravenous administration. She is author and co-author of more than 120 research papers as well as over 20 review papers and book chapters on nanoparticle preparation, characterization methods, and on the application of nanoparticles as drug delivery systems. Dr. Vauthier has spoken at numerous conferences and has presented over 100 communications.