The Potential of Intermittent Fasting in Age-related Diseases and Precision Anti-aging Therapeutics

The Potential of Intermittent Fasting in Age-related Diseases and Precision Anti-aging Therapeutics takes an in-depth look at the beneficial and efficacious role of Intermittent Fasting (IF) in a wide array of aging-associated diseases. It provides a comprehensive resource that not only outlines the potential benefits and future research directions but also delves into the limitations and nuances of IF in managing these conditions. The book is divided sections and begins by covering the fundamentals of aging and the effects of IF. Subsequent sections examine the physiological impact IF has on aging; its potential influence on stress resistance, heart, gut, and overall health optimization; social and ethical considerations as a therapeutic strategy; bridging IF research findings and clinical practice; and the potential integration and application of IF into age-related diseases treatment. Offering a consolidated and scientifically grounded perspective aimed at equipping readers with a balanced understanding, this book serves as a go-to reference for researchers and clinicians alike seeking clear and accurate insights into how IF can positively influence the health and longevity of the aging population.

• Offers comprehensive coverage of the intricacies of IF and its promising implications in age-related diseases and precision antiaging therapeutics
• Explores IF's mechanistic insights and mode of action in disorders associated with aging and lifestyle changes
• Discusses cutting-edge advancements in biomedicine and treatment strategies linked to aging-related conditions through IF-focused research

Dr. Abhishek Kumar Singh is Associate Professor at Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, India. Dr. Singh obtained his PhD from the CSIR-Indian Institute of Toxicology Research, India, and brings more than a decade of research experience in neurodegeneration and neuroprotection. His research focuses on developing anti-aging strategies targeting autophagy pathways in brain aging and age-related neurodegenerative disorders. Dr. Singh has corresponding teaching experience in biomaterials, bioprocess engineering, and gene therapy.

Dr. Jitendra Kumar Sinha is a neuroscientist and Associate Professor at the Symbiosis Institute of Health Sciences (SIHS), Symbiosis International (Deemed University), Pune, India. He received his PhD from the ICMR–National Institute of Nutrition and has undertaken internationally collaborative research at institutions in Italy, Australia, and India. With over two decades of experience in research and teaching, his work focuses on the neurobiology of ageing and obesity, nutritional neuroscience, neuropsychiatric disorders, and neuropharmacology. He has made notable contributions to animal models of ageing and epilepsy, particularly in understanding oxidative stress, DNA damage, and biomarkers of accelerated ageing. Dr. Sinha has authored more than 150 research articles and book chapters and actively contributes to the scientific community as an editor and reviewer. He is also deeply engaged in mentoring and academic capacity building.

Affiliations and expertise

Symbiosis Institute of Health Sciences (SIHS), Symbiosis International (Deemed University), India

Dr. Raviraja Seetharam is Professor and Head of Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, India. Dr. Seetharam obtained his MSc and PhD in Biosciences from Mangalore University, India, and completed post-doctoral research at Mount Allison University, Canada, and Albert Einstein College of Medicine, USA. He brings nearly 30 years of research experience in regenerative medicine, microbiology, and cell and molecular biology. He is a lifetime member of the International Society for Stem Cell Research (ISSCR), USA.