Skin physiology assessment is moving rapidly from a descriptive approach to a deeper understanding of biophysical and biochemical processes in the stratum corneum, e.g. on stratum corneum barrier function as well on stratum corneum hydration. The research with bioengineering methods offers now reliable and reproducible approaches for product testing in the pharmaceutical and cosmetic industry as well as in basic research. This cookbook is intended to give basic information regarding skin physiology, the assessment of skin functions in controlled studies using non-invasive biophysical instruments. It provides basic knowledge on how to plan, perform and evaluate scientific studies. The authors are recognized expert in the field and provide comprehensive chapters with specific emphasis on the practical aspects of non-invasive measurements.
Assessment of skin physiology is moving rapidly away from a purely descriptive approach as we gain a deeper understanding of biophysical and biochemical processes in the stratum corneum, such as those relating to its barrier function and hydration. As a result of research utilizing bioengineering methods, reliable and reproducible approaches are now available for product testing in the pharmaceutical and cosmetic industry as well as in basic research. This book examines in detail all aspects of cosmetic testing – legal, general, and practical. After discussion of regulatory and ethical issues and guidelines, essential guidance is provided on the planning, performance, and evaluation of scientific studies in skin physiology. The topics addressed range from laboratory and staffing requirements through to testing devices and methods, factors influencing measurements, and study design. In addition, detailed information is provided on test settings for a range of cosmetic products. All ofthe authors are recognized experts in their field. This book will be invaluable to researchers, students, and medical staff in explaining how best to assess skin functions in controlled studies using non-invasive biophysical instruments.