Prediction of Protein Structures, Functions, and Interactions

ISBN 10: 0470517670 / ISBN 13: 9780470517673

Published by Wiley, 2008

About this Item

Ancien livre de bibliothèque avec équipements. Edition 2008. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 2008. Ammareal gives back up to 15% of this item's net price to charity organizations.

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Bibliographic Details

• Title: Prediction of Protein Structures, Functions, and Interactions
• Publisher: Wiley
• Publication Date: 2008
• Language: English
• ISBN 10: 0470517670
• ISBN 13: 9780470517673
• Binding: Hardcover
• Condition: Très bon

About this title

Synopsis

The growing flood of new experimental data generated by genome sequencing has provided an impetus for the development of automated methods for predicting the functions of proteins that have been deduced by sequence analysis and lack experimental characterization.

Prediction of Protein Structures, Functions and Interactions presents a comprehensive overview of methods for prediction of protein structure or function, with the emphasis on their availability and possibilities for their combined use. Methods of modeling of individual proteins, prediction of their interactions, and docking of complexes are put in the context of predicting gene ontology (biological process, molecular function, and cellular component) and discussed in the light of their contribution to the emerging field of systems biology. Topics covered include:

• first steps of protein sequence analysis and structure prediction
• automated prediction of protein function from sequence
• template-based prediction of three-dimensional protein structures: fold-recognition and comparative modelling
• template-free prediction of three-dimensional protein structures
• quality assessment of protein models
• prediction of molecular interactions: from small ligands to large protein complexes
• macromolecular docking
• integrating prediction of structure, function, and interactions

Prediction of Protein Structures, Functions and Interactions focuses on the methods that have performed well in CASPs, and which are constantly developed and maintained, and are freely available to academic researchers either as web servers or programs for local installation. It is an essential guide to the newest, best methods for prediction of protein structure and functions, for researchers and advanced students working in structural bioinformatics, protein chemistry, structural biology and drug discovery.  

About the Author

Professor Bujnicki is head of the Laboratory of Bioinformatics and Protein Engineering at the International Institute of Molecular and Cell Biology, Warsaw, Poland. He is the editor of “Practical Bioinformatics" (Springer-Verlag, 2004).