Predictive Approaches in Drug Discovery and Development Biomarkers and In Vitro / In Vivo Correlations

Williams, J. Andrew (Editor)/ Lalonde, Richard (Editor)/ Koup, Jeffrey R. (Editor)/ Christ, David D. (Editor)/ Ekins, Sean (Editor)

ISBN 10: 0470170832 / ISBN 13: 9780470170830

Published by John Wiley & Sons Inc, 2012

About this Item

1st edition. 408 pages. 9.25x6.50x0.75 inches. In Stock.

Seller Inventory # x-0470170832

Bibliographic Details

• Title: Predictive Approaches in Drug Discovery and Development Biomarkers and In Vitro / In Vivo Correlations
• Publisher: John Wiley & Sons Inc
• Publication Date: 2012
• Language: English
• ISBN 10: 0470170832
• ISBN 13: 9780470170830
• Binding: Hardcover
• Condition: Brand New
• Weight: 0.72 kilograms

About this title

Synopsis

Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers.  Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers.  Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.

About the Author

J. Andrew Williams, PHD, is Director of Translational Oncology at Pfizer Oncology.

Richard Lalonde, PharmD, is Vice President and Global Head of Clinical Pharmacology at Pfizer.

Jeffrey Koup, PharmD, is a consultant for PKPD modeling and the owner of Lakeside PKPD, LLC.

David D. Christ, PHD, is a consultant with SNC Partners LLC.