Prefrontal Cortex Cognitive Deficits in Children Treated Early and Continuously for PKU

Diamond, Adele (Editor), and Prevor, Meredith (Editor), and Callender, Glenda (Editor)

ISBN 10: 0226144771 / ISBN 13: 9780226144771

Published by University of Chicago Press, Chicago, IL, 1997

About this Item

Trade paperback (US). Glued binding. 220 p. Contains: Illustrations. Monographs of the Society for Research in Child Development; . Audience: General/trade. Very good. light shelfwear, no ownership marks.

Seller Inventory # Alibris.0021288

Bibliographic Details

• Title: Prefrontal Cortex Cognitive Deficits in Children Treated Early and Continuously for PKU
• Publisher: University of Chicago Press, Chicago, IL
• Publication Date: 1997
• Language: English
• ISBN 10: 0226144771
• ISBN 13: 9780226144771
• Binding: Trade paperback

About this title

Synopsis

The metabolic disorder phenylketonuria (PKU) is the most common biochemical cause of mental retardation, and affects roughly one in 10,000 children. Bridging basic neuroscience research and clinical studies, this longitudinal study (a) provides evidence that cognitive deficits result from even moderate amino acid imbalances considered acceptable under the standard treatment for PKU, (b) characterizes the nature of those cognitive deficits, and (c) identifies their biological cause. The authors discuss possible steps to correct the problem, and possible implications of the findings for children with other developmental disabilities, such as attention deficit disorder.