A Preliminary Study On Association Of Adiponectin Gene Polymorphism: With Type 2 Diabetes Mellitus Patients In Chidambaram-cuddalore-district Tamilnadu, India

Prithiviraj, Nagarajan

ISBN 10: 3659310794 / ISBN 13: 9783659310799

Published by LAP LAMBERT Academic Publishing, 2012

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Bibliographic Details

• Title: A Preliminary Study On Association Of Adiponectin Gene Polymorphism: With Type 2 Diabetes Mellitus Patients In Chidambaram-cuddalore-district Tamilnadu, India
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2012
• Language: English
• ISBN 10: 3659310794
• ISBN 13: 9783659310799
• Binding: Paperback
• Condition: Like New
• Book Type: book

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Synopsis

Diabetes mellitus is widely recognized as one of the leading cause of death.In 2008,it was the seventh leading cause of death.In 2006,among people aged 65 years or older,heart disease was noted on 68 percent of diabetes.Diabetes is associated with long term complications that affect most parts of the body.Uncontrolled diabetes can complicate pregnancy,and birth defects are common in babies born to women with diabetes.Adiponectin,(ADP) is a protein produced by adipose tissue,which regulates metabolisms of lipids and glucose and also influences the body response to insulin).It has been studied in Asian Indians and reported that there was an association with polymorphism of Adiponectin gene and diabetes mellitus.In the present study Blood samples were collected from 20 normal and 20 diabetic patients in the age groups of 40-65 years of both sexes. Single nucleotide polymorphism (SNP) was found in G allele of ADP 45 intron of adiponectin gene.Our study shows that there was a significant association of G allele with type 2 diabetes mellitus.

About the Author

N.Prithiviraj researcher obtained his M.sc Biotechnology,P.G.Diploma in clinical research.Doing Ph.D in Marine Biotechnology in Annamalai university C.A.S Marine Biology india.He has attended 15 conference presented 13 papers and published 10 research papers in International journals,worked as lecturer in srinivasan arts & science,perambalur india.