Principles and Applications of Up-converting Phosphor Technology

This book presents an overview of up-converting phosphor (UCP), including UCP preparation, development of the rapid detection strips and UCP industrialization. It also discusses the wide clinical applications of this technology, such as in food poisoning, infectious diseases, drug-abuse and disaster rescue, where rapid point-of-care testing is often critical. Conventional testing methods are mainly based on gold immunochromatography, which relies heavily on results being read with the naked eye. However, up-converting phosphor technology (UPT) employs UCP particles as labels for rapid target detection. Unlike other conventional fluorescence techniques, UCP is excited by infrared light and emitted visible light. This anti-stokes phenomenon provides this special label with significant advantages, including zero background detection, high resistance to environmental influences (e.g. pH, salts, sample contamination), high sensitivity and quantitative detection.

Systematically summarizing UCP technology and its wide applications, this book is a valuable resource for researchers and technicians in the field.

Dr. Ruifu Yang is a Professor at the Beijing Institute of Microbiology and Epidemiology and the Chief Scientist for the National Basic Research Program (973 Program). He is also the vice president of the Chinese Society for Microbiology. His research focuses on investigating bacterial pathogenesis using genomics- and proteomics-based techniques. He has published more than 200 articles on leading international journals, such as the New England Journal of Medicine, Nature Genetics, PNAS, Clinical Infectious Diseases, and ISME Journal etc.