Principles and Practice of Particle Therapy

Although radiation has been used therapeutically for over 100 years, the field of radiation oncology is currently in the midst of a renaissance, particularly with regards to the therapeutic use of particles. Over the past several years, access to particle therapy, whether it be proton therapy or other heavy ion therapy, has increased dramatically. Principles and Practice of Particle Therapy is a clinically oriented resource that can be referenced by both experienced clinicians and those who are just beginning their venture into particle therapy.

Written by a team with significant experience in the field, topics covered include:

• Background information related to particle therapy, including the clinically relevant physics, radiobiological, and practical aspects of developing a particle therapy program
• “Niche” treatments, such as FLASH, BNCT, and GRID therapy
• The simulation process, target volume delineation, and unique treatment planning considerations for each disease site
• Less commonly used ions, such as fast neutrons or helium

Principles and Practice of Particle Therapy is a go-to reference work for any health professional involved in the rapidly evolving field of particle therapy.

Timothy D. Malouff is an emerging leader in particle therapy. He has published and presented extensively on a variety of topics related to particle therapy, including proton therapy, carbon ion therapy, boron neutron capture therapy, and other heavy ion therapy. Dr. Malouff’s research goals include critically evaluating and expanding the indications for “novel” radiation modalities, including particle therapy. Outside of the clinic, Dr. Malouff enjoys spending time with his family.

Daniel M. Trifiletti as an international leader in radiation oncology and stereotactic radiosurgery at the Mayo Clinic, the research of Dr. Trifiletti includes numerous clinical studies involving radiation, surgery and drug therapies in the treatment of tumors. Dr. Trifiletti’s short-term research goals focus on describing the impact of radiation on the priming of the brain tumor microenvironment. Discovering the biological underpinnings of radiation priming will allow for novel, “game-changing” cancer therapies, rapid translation to early-stage clinical trials and, ultimately, improved outcomes in patients with fatal diseases.