Probability Models for DNA Sequence Evolution.

Rick Durrett

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Language: English

Published by New York, NY, U.S.A. Springer Verlag, 2002

038795435X / 9780387954356

Series: Book 6 of 35 - Probability and Its Applications

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Seller: CSG Onlinebuch GMBH, Darmstadt, GermanyCSG Onlinebuch GMBH

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" Gebraucht - Sehr gut Zustand: Sehr gut, VIII, 240 pp. 62 figs. About this book: Our basic question is: Given a collection of DNA sequences, what underlying forces are responsible for the observed patterns of variability? To approach this question we introduce and analyze a number of probability models: the Wright-Fisher model, the coalescent, the infinite alleles model, and the infinite sites model. We study the complications that come from nonconstant population size, recombination, population subdivision, and three forms of natural selection: directional selection, balancing selection, and background selection. These theoretical results set the stage for the investigation of various statistical tests to detect departures from \"neutral evolution.\" The final chapter studies the evolution of whole genomes by chromosomal inversions, reciprocal translocations, and genome duplication. Throughout the book, the theory is developed in close connection with data from more than 60 experimental studies from the biology literature that illustrate the use of these results. This book is written for mathematicians and for biologists alike. We assume no previous knowledge of concepts from biology and only a basic knowledge of probability: a one semester undergraduate course and some familiarity with Markov chains and Poisson processes. Rick Durrett received his Ph.D. in operations research from Stanford University in 1976. He taught in the UCLA mathematics department before coming to Cornell in 1985. He is the author of six books and 125 research papers, and is the academic father of more than 30 Ph.D. students. His current interests are the use of probability models in genetics and ecology, and decreasing the mean and variance of his golf. Written for researchers, graduate students. ".

Seller Inventory # 18113

Title
Probability Models for DNA Sequence Evolution.
Author
Rick Durrett
Publisher
New York, NY, U.S.A. Springer Verlag
Publication year
2002
Condition
Sehr gut
Binding
Gebunden
Language
English
ISBN 10
038795435X
ISBN 13
9780387954356
Series
Book 6 of 35: Probability and Its Applications

CSG Onlinebuch GMBH

Darmstadt, Germany

5-star seller

AbeBooks seller since September 6, 2022

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