Probing Bioactive Mechanisms (Acs Symposium Series)

This is the first book of its kind to bring together the seemingly diverse fields of medicinal chemistry, agrochemicals, and chemical toxicology with an examination of their common mechanistic ground. This volume explores how a variety of statistical and computer modeling techniques can be used to design biologically active mechanisms, elucidate the pertinent structure-activity relationships, and define the characteristics of receptor and receptor-ligand interactions. An introductory section focuses on historical perspectives, with subsequent chapters providing broad coverage of agrochemical mechanisms, drug mechanisms, and toxicity mechanisms.

Philip S. Magee, BIOSTAR Research Project. Douglas R. Henry, Molecular Design Limited. John H. Block, Oregon State University.