Process Development of Amlodipine and Olmesartan Medoxomil Tablets: Process Development of Amlodipine and Olmesartan Medoxomil Tablets 10/40 Mg

Behera, Gayatri; Behera, Jayashree; Barik, Binapani

ISBN 10: 6203409332 / ISBN 13: 9786203409338

Published by LAP LAMBERT Academic Publishing, 2021

About this Item

Seller Inventory # I-9786203409338

Bibliographic Details

• Title: Process Development of Amlodipine and Olmesartan Medoxomil Tablets: Process Development of Amlodipine and Olmesartan Medoxomil Tablets 10/40 Mg
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2021
• Language: English
• ISBN 10: 6203409332
• ISBN 13: 9786203409338
• Binding: Soft cover
• Condition: New

About this title

Synopsis

The present study was focused on process development of amlodipine and olmesartan medoxomil tablet 10/40mg. Amlodipine and Olmesartan medoxomil is a combination of a calcium channel blocker and an angiotensin II receptor antagonist used to treat high blood pressure . The Content uniformity was found of both the drugs were performed. Release study was conducted in pH 6.8 buffer media. Furthermore, dissolution profile comparison was carried out using similarity factor (f2) and the similarity factor of Amlodipine and Olmesartan Medoxomil found to be 73. Other studies Like DSC and FTIR studies reported compatibility of Amlodipine besylate with excipients like Cross Carmel lose sodium was performed shows no chemical interaction between drug and excipients. Dissolution profile of Test and Reference standard found to be similar, Similarity factor (f2) is 73.