Processing and Dissolution enhancement of Newer NSAID's

Spherical agglomeration is a particle engineering technique by which crystallization and agglomeration can be carried out simultaneously in one step to transform crystals directly into a compacted spherical form. Spherical crystallization technique transforms directly the fine particles produced in the crystallization or in the reaction process into a spherical shape. Agglomerates exhibit improved secondary characteristics like flow ability and compressibility so that direct tableting or coating is possible without further processing.