Prodrug Designing of NSAIDs : "Design, Synthesis and Biological Screening of Carrier Linked Prodrugs of Potent NSAIDs"

Language: English

Published by LAP Lambert Academic Publishing, 2012

3843370575 / 9783843370578

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Separation of therapeutic effects from toxicity is a valuable goal in the drug development process. Prodrug design is a part of the general drug discovery process, in which a unique combination of therapeutically active substances is observed to have desirable pharmacological effects. In human therapy prodrug designing has given successful results in overcoming undesirable properties like absorption, nonspecificity, and poor bioavailability and GIT toxicity. Prodrug design is opening new doors in the challenging field of drug discovery, revolutionizing the art of Drug development.In this dissertation work, Synthesis of amide prodrugs of Niflumic acid and Ketoprofen with Glucosamine was achieved in good yields by a simple technique.Here prodrug approach has been successfully applied in attaining the goal of minimized gastrointestinal toxicity without loss of desired anti-inflammatory activities of the drug.

Seller Inventory # 9783843370578

Title
Prodrug Designing of NSAIDs : "Design, Synthesis and Biological Screening of Carrier Linked Prodrugs of Potent NSAIDs"
Author
Smita Patil
Publisher
LAP Lambert Academic Publishing
Publication year
2012
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3843370575
ISBN 13
9783843370578
Item weight
173 grams
Dimensions
220x150x7 mm

AHA-BUCH GmbH

Einbeck, Germany

5-star seller

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