Prognostic and Predictive Value of p53 (European School of Oncology Scientific Updates, Volume 1)
Language: English
Published by Amsterdam: Elsevier, 1997
- Hardcover
- Used
Seller: Old Line Books, Severna Park, MD, U.S.A.Old Line Books
AbeBooks seller since March 13, 1998
Condition: Used - Near fine
US$ 30.00
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Seller Inventory # 1253
- Title
- Prognostic and Predictive Value of p53 (European School of Oncology Scientific Updates, Volume 1)
- Author
- Klijn, J.G.M. (ed)
- Publisher
- Amsterdam: Elsevier
- Publication year
- 1997
- Condition
- Near Fine
- Dust jacket
- No Jacket
- Binding
- Hardcover
- Language
- English
- ISBN 10
- 044482832X
- ISBN 13
- 9780444828323
- Seller catalogs
- Medicine
This cellular protein was discovered in 1979 by a number of investigators independently and alterations of p53 or its product are observed in about half of all cancers.
In the early 1980s, several laboratories initially demonstrated dominant oncogenic activities of the gene. Then, in 1989, p53 was recognised as a classic tumour suppressor gene based on the results of various studies by different research groups.
Since the detection of the gene and its product, various important functions have been described. The gene appears to be involved in cell cycle control, DNA repair, apoptosis, cellular differentiation, senescence and angiogenesis.
In view of the rapidly increasing importance of p53, a Task Force Meeting was organised by the European School of Oncology
"Synopsis" may belong to another edition of this title.
Old Line Books
Severna Park, MD, U.S.A.
AbeBooks seller since March 13, 1998
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Old Line Books
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