Title: Protective and Pathological Immune Responses in the CNS (Current Topics in Microbiology and Immunology, 265)
Publisher: Springer
Publication Date: 2002
Language: English
ISBN 10: 354042668X
ISBN 13: 9783540426684
Binding: Hardcover
Condition: New

About this title

Synopsis

In spite of the protection of the CNS there are situations where immune responses occur due to different disease processes. While antigen-specific cells of the adaptive immune response are not normally functional in the CNS tissue, CNS resident cells respond to infection or insult. One mechanisms is through the induction of apoptosis in virus infected neurons, which may be protective or pathogenic depending on the extent of cell death.

From the Back Cover

It is well known that the CNS is normally protected from immune effectors because of the potential of irreversible damage to the nervous tissue. Nevertheless, there are situations where immune responses occur in the CNS due to different disease processes. Some of these responses are purely pathogenic while others clear or contain disease causing pathogens. In this volume, the mechanisms responsible for the varied outcomes are compared and contrasted.

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