Protein Dynamics : A Study of the Model-free Analysis of NMR Relaxation Data

Language: English

Published by VDM Verlag Dr. Müller, 2008

3639057627 / 9783639057621

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Functionally, proteins are the most important building blocks of life. Their diverse biological activities are often intricately linked to their internal mobility. Model-free analysis of NMR relaxation data is the most widely employed method for experimentally studying protein dynamics at the atomic level. This book investigates all aspects of the model-free data analysis chain, and shows how to obtain a much improved dynamic description of macromolecules. Using statistical model selection the choice of model-free model is overhauled to uncover previously hidden motions, failed model-free models are eliminated, the optimisation of the model-free models is significantly improved to increase the accuracy of the final results and a new protocol is presented for the optimisation of the global model which reverses the current logic thereby solving the hidden motion problem and the issues of artificial chemical exchange and artificial nanosecond motions. The advances presented here should be of interest to anyone studying the internal motions of complex molecules.…

Seller Inventory # 9783639057621

Title
Protein Dynamics : A Study of the Model-free Analysis of NMR Relaxation Data
Author
Edward d''Auvergne
Publisher
VDM Verlag Dr. Müller
Publication year
2008
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3639057627
ISBN 13
9783639057621
Item weight
552 grams
Dimensions
220x150x33 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

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