Protein Interaction Networks: Computational Analysis

Zhang, Aidong

ISBN 10: 0521888956 / ISBN 13: 9780521888950

Published by Cambridge University Press (edition 1), 2009

About this Item

It's a preowned item in good condition and includes all the pages. It may have some general signs of wear and tear, such as markings, highlighting, slight damage to the cover, minimal wear to the binding, etc., but they will not affect the overall reading experience.

Seller Inventory # 0521888956-11-1

Bibliographic Details

• Title: Protein Interaction Networks: Computational Analysis
• Publisher: Cambridge University Press (edition 1)
• Publication Date: 2009
• Language: English
• ISBN 10: 0521888956
• ISBN 13: 9780521888950
• Binding: Hardcover
• Edition: 1.
• Condition: Good

About this title

Synopsis

The analysis of protein-protein interactions is fundamental to the understanding of cellular organization, processes, and functions. Recent large-scale investigations of protein-protein interactions using such techniques as two-hybrid systems, mass spectrometry, and protein microarrays have enriched the available protein interaction data and facilitated the construction of integrated protein-protein interaction networks. The resulting large volume of protein-protein interaction data has posed a challenge to experimental investigation. This book provides a comprehensive understanding of the computational methods available for the analysis of protein-protein interaction networks. It offers an in-depth survey of a range of approaches, including statistical, topological, data-mining, and ontology-based methods. The author discusses the fundamental principles underlying each of these approaches and their respective benefits and drawbacks, and she offers suggestions for future research.

About the Author

Dr Aidong Zhang is a professor in the Department of Computer Science and Engineering at the State University of New York at Buffalo and the director of the Buffalo Center for Biomedical Computing (BCBC). She is an author of more than 190 research publications and has served on the editorial boards of the International Journal of Bioinformatics Research and Applications (IJBRA), ACM Multimedia Systems, the International Journal of Multimedia Tools and Applications, the International Journal of Distributed and Parallel Databases, and ACM SIGMOD DiSC (Digital Symposium Collection). Dr Zhang is a recipient of the National Science Foundation CAREER Award and SUNY (State University of New York) Chancellor's Research Recognition Award.