Protein Misfolding, Aggregation and Conformational Diseases

ISBN 10: 038736529X / ISBN 13: 9780387365299

Published by Springer, 2007

About this Item

pp. 580.

Seller Inventory # 26283310

Bibliographic Details

• Title: Protein Misfolding, Aggregation and Conformational Diseases
• Publisher: Springer
• Publication Date: 2007
• Language: English
• ISBN 10: 038736529X
• ISBN 13: 9780387365299
• Binding: Hardcover
• Condition: New

About this title

Synopsis

The second volume continues to fill the gap in protein review and protocal literature while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.

From the Back Cover

Protein Misfolding, Aggregation and Conformational Diseases, Part B: Molecular Mechanisms of Conformational Diseases, is a comprehensive volume providing a broad and detailed discussion of the relationships of protein misfolding and aggregation with the pathogenesis of numerous conformational diseases. While the Part A was dedicated to the description of the general mechanisms underlying protein misfolding, aggregation, and development of protein deposition disorders, this volume summarizes recent achievements in the understanding of the molecular mechanisms of conformational diseases. Research indicates that these mechanisms are highly diverse and range from the altered protein structure leading to the enhanced propensity for aggregation/deposition or the impaired functions and ending with changes in supra-molecular structures or posttranslational modification. Protein Misfolding, Aggregation and Conformational Diseases, Part B: Molecular Mechanisms of Conformational Diseases, is an ideal book for pharmaceutical scientists, molecular and cellular biologists, biochemists, immunologists, protein scientists, and biophysicists.