Hardcover. This detailed volume explores robust analytical workflows for post-translational modification (PTM) analysis in both basic and translational contexts. After brief foundational reviews of the field, the book delves into detailed experimental and computational protocols for traditional bottom-up strategies and top-down proteoform analysis, as well as PTM analysis of biotherapeutic proteins, reflecting the growing emphasis on PTMs as critical quality attributes in biologic drug development and regulation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.Authoritative and practical, Protein Post-Translational Modifications: Methods and Protocols serves as a foundational and forward-looking resource to support and inspire continued exploration in this rapidly evolving field. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

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Bibliographic Details

Title: Protein Post-Translational Modifications (Hardcover)
Publisher: Springer-Verlag New York Inc.
Publication Date: 2026
Language: English
ISBN 10: 107165165X
ISBN 13: 9781071651650
Binding: Hardcover
Condition: new

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This detailed volume explores robust analytical workflows for post-translational modification (PTM) analysis in both basic and translational contexts. After brief foundational reviews of the field, the book delves into detailed experimental and computational protocols for traditional bottom-up strategies and top-down proteoform analysis, as well as PTM analysis of biotherapeutic proteins, reflecting the growing emphasis on PTMs as critical quality attributes in biologic drug development and regulation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.

Authoritative and practical, Protein Post-Translational Modifications: Methods and Protocols serves as a foundational and forward-looking resource to support and inspire continued exploration in this rapidly evolving field.

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