Protein Structure and Protein Engineering

Robert Huber

ISBN 10: 3642741754 / ISBN 13: 9783642741753

Published by Springer Berlin Heidelberg, 2013

About this Item

Druck auf Anfrage Neuware - Printed after ordering - Protein engineering has had considerable impact on basic and applied research in biochemistry and molecular biology. It is already in use as a tool in molecular biology, but it is beginning to strongly influence the planning of experiments in biology everywhere, and, with even fur ther-reaching consequences, the appointment politics in research in stitutions and industries. Protein engineering, perhaps more than any other methods of protein analysis and peptide synthesis, has shown that proteins are organic molecules governed by the universal laws of chemistry and physics. How ever, as was the case with other new powerful methods and techniques, protein engineering tempts to an exploration of its limitations and thus generates more questions than it answers. The 39th Mosbacher Colloquium on Protein Structure and Protein Engi neering is not the first conference on this topic and it will not be the last. The important issues are obviously techniques of protein en gineering, examples of application, and the basic framework of protein structure and stability within which reasonable experiments can be de signed; conversely also, what we can learn about protein structure, dynamics, and folding from such experiments. Experiments in this direc tion aim at elucidating the folding code in the long run, but help to exploit the role of individual amino acid residues in catalysis, pro tein stability, and binding specificity in selected proteins now.

Seller Inventory # 9783642741753

Bibliographic Details

• Title: Protein Structure and Protein Engineering
• Publisher: Springer Berlin Heidelberg
• Publication Date: 2013
• Language: English
• ISBN 10: 3642741754
• ISBN 13: 9783642741753
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 244W x 170H x 9D millimeters 244 millimeters width by 170 millimeters height by 9 millimeters depth
• Weight: 269 grams

About this title

Synopsis

Protein engineering has had considerable impact on basic and applied research in biochemistry and molecular biology. It is already in use as a tool in molecular biology, but it is beginning to strongly influence the planning of experiments in biology everywhere, and, with even fur­ ther-reaching consequences, the appointment politics in research in­ stitutions and industries. Protein engineering, perhaps more than any other methods of protein analysis and peptide synthesis, has shown that proteins are organic molecules governed by the universal laws of chemistry and physics. How­ ever, as was the case with other new powerful methods and techniques, protein engineering tempts to an exploration of its limitations and thus generates more questions than it answers. The 39th Mosbacher Colloquium on Protein Structure and Protein Engi­ neering is not the first conference on this topic and it will not be the last. The important issues are obviously techniques of protein en­ gineering, examples of application, and the basic framework of protein structure and stability within which reasonable experiments can be de­ signed; conversely also, what we can learn about protein structure, dynamics, and folding from such experiments. Experiments in this direc­ tion aim at elucidating the folding code in the long run, but help to exploit the role of individual amino acid residues in catalysis, pro­ tein stability, and binding specificity in selected proteins now.