Proteomic Analysis of Kir6.2 Using Bioinformatics Software Tools

Paulraj Sugapriya Menaga

ISBN 10: 3659513857 / ISBN 13: 9783659513855

Published by LAP LAMBERT Academic Publishing, 2014

About this Item

Proteomic Analysis of Kir6.2 Using Bioinformatics Software Tools | Paulraj Sugapriya Menaga | Taschenbuch | 104 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659513855 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Seller Inventory # 105466687

Bibliographic Details

• Title: Proteomic Analysis of Kir6.2 Using Bioinformatics Software Tools
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2014
• Language: English
• ISBN 10: 3659513857
• ISBN 13: 9783659513855
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 7D millimeters 220 millimeters width by 150 millimeters height by 7 millimeters depth
• Weight: 173 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

KATP Channels couple glucose metabolism to membrane potential and thus play a central role in glucose stimulated insulin secretion. Genetic mutations in the genes encoding the channel subunits (Kir 6.2) can cause Congenital Hyperinsulinism (CHI). BLAST and FASTA similarity searches reveals the closely relatedness of Kir6.2 with other inwardly rectifying K+ channel family of proteins. The phylogenetic analysis showed the evolutionary relationship of various mammals with reference to Kir6.2. The secondary structure prediction, Tranmembrane and hydropathy prediction reveals the Kir6.2 contained more number of helical regions.Further, the Kir6.2 protein contains motifs which are responsible for Prokaryotic membrane lipoprotein lipid attachment site, cAMP and cGMP dependent protein kinase, casein kinase II and Protein Kinase C phosphorylation site.

About the Author

Sugapriyamenaga Paulraj is having 9 years of teaching experience and currently working as Assistant Professor in Biotechnology, ANJAC, Sivakasi. She completed UG Biochemistry, PG Integrated Biology, ADBI, PGDCA & MPhil in Biotech.Received two TNSCST Projects & guided 20 M.Sc. student Projects. The Author is having good knowledge in Bioinformatics.