RNA Editing : Current Research and Future Trends

Stefan Maas

ISBN 10: 1908230231 / ISBN 13: 9781908230232

Published by Caister Academic Press Limited, 2013

About this Item

nach der Bestellung gedruckt Neuware - Printed after ordering - Cellular editing of RNA can lead to the recoding of expressed sequences before they mature to their functional gene products, such as proteins or regulatory RNAs, and represents a hidden layer of genetic information and regulation. Often, the recoding events are essential for the normal function of the gene product (for example creating an open reading frame), in other cases RNA editing creates additional variation and phenotypic diversity since both the edited and the non-edited versions of the product are functional and co-exist. It is necessary to understand the mechanisms of RNA editing in order to elucidate the overall physiological impact of this phenomenon. This major new work presents an up-to-date overview of RNA editing. All the chapters here have been written by experts in the various research areas and describe key recent findings as well as exploring current frontiers in the mechanisms and functional roles of RNA editing. The chapters span the editing of protein coding mRNAs, small regulatory RNAs, tRNAs and non-coding sequences. Also included are studies employing bioinformatics to identify and predict RNA editing sites as well as the evolution of RNA modification. An essential text for anyone interested in RNA editing and modification, RNA structure and function, post-transcriptional regulation, and the regulation of gene expression and a recommended purchase for molecular biology libraries.

Seller Inventory # 9781908230232

Bibliographic Details

• Title: RNA Editing : Current Research and Future Trends
• Publisher: Caister Academic Press Limited
• Publication Date: 2013
• Language: English
• ISBN 10: 1908230231
• ISBN 13: 9781908230232
• Binding: Buch
• Condition: Neu
• Dimensions: 260W x 183H x 18D millimeters 260 millimeters width by 183 millimeters height by 18 millimeters depth
• Weight: 683 grams

About this title

Synopsis

Cellular editing of RNA can lead to the recoding of expressed sequences before they mature to their functional gene products, such as proteins or regulatory RNAs, and represents a hidden layer of genetic information and regulation. Often, the recoding events are essential for the normal function of the gene product (for example creating an open reading frame), in other cases RNA editing creates additional variation and phenotypic diversity since both the edited and the non-edited versions of the product are functional and co-exist. It is necessary to understand the mechanisms of RNA editing in order to elucidate the overall physiological impact of this phenomenon. This major new work presents an up-to-date overview of RNA editing. All the chapters here have been written by experts in the various research areas and describe key recent findings as well as exploring current frontiers in the mechanisms and functional roles of RNA editing. The chapters span the editing of protein coding mRNAs, small regulatory RNAs, tRNAs and non-coding sequences. Also included are studies employing bioinformatics to identify and predict RNA editing sites as well as the evolution of RNA modification. An essential text for anyone interested in RNA editing and modification, RNA structure and function, post-transcriptional regulation, and the regulation of gene expression and a recommended purchase for molecular biology libraries.