Reaction Patterns of the Lymph Node: Part 2 Reactions Associated with Neoplasia and Immune Deficient States (Current Topics in Pathology)

Grundmann, E., E. Vollmer D.V. Ablashi u. a.:

ISBN 10: 3540522883 / ISBN 13: 9783540522881

Published by Springer, 1991

About this Item

234 Seiten; ohne Schutzumschlag, Eintrag/Stempel vorne im Buch, Artikel stammt aus Nichtraucherhaushalt! DF6361 Sprache: Deutsch Gewicht in Gramm: 500.

Seller Inventory # 1313345

Bibliographic Details

• Title: Reaction Patterns of the Lymph Node: Part 2 Reactions Associated with Neoplasia and Immune Deficient States (Current Topics in Pathology)
• Publisher: Springer
• Publication Date: 1991
• Language: German
• ISBN 10: 3540522883
• ISBN 13: 9783540522881
• Binding: hardcover
• Condition: Gut
• Weight: 500 grams
• Seller catalogs:
  • Varia

About this title

Synopsis

This second volume reports on the reaction patterns of lymph nodes in neoplastic and immunodeficient diseases. Based on the contents of volume 1, it presents a detailed survey of lymph node structures and their cellular components under these conditions. The patterns of nodal reactions to the development and spread of cancer have recently been investigated and discussed by several authors. Here, the immediate interactions between tumor tissue and the regional nodes have been assessed in experimental models and in human material. Using modern morphological methods such as im­ munohistochemistry on the light and electron microscopic level, new insights have been gained into the stepwise process of lymphogenous metastasis. Macrophages/reticulum cells were found to playa signifi­ cant role in this process, which is duly emphasized. Based on appro­ priate animal models, one chapter focuses on various subtypes of these cellular elements and their role in the two separate phases of tumor spread and the development of true metastases. The induction of fibronectin in lymph nodes is effected by tumor cells forming a special part of the extracellular matrix. The multifunctional fibronec­ tin molecule serves as a mediator between tumor cells and fibroblasts, furthering the formation of tumor stroma. This volume also contains a comprehensive survey of primary im­ munodeficiency syndromes and their nodal manifestations, reference being made to the most recent immunological knowledge.