Real-Space Methods to Solve Protein Structures : Improved Density-Modification Techniques for Phasing and Phase Extension in Protein Crystallography.

Language: English

Published by LAP LAMBERT Academic Publishing, 2010

3838372689 / 9783838372686

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - This book reproduces work written for a PhD thesis. It introduces new theoretical methods for the solution of protein structures through the processing and interpretation of crystallographic data coming from high-resolution X-ray diffraction experiments. Only data for the native protein are used, i.e. the procedure here explained and tested implies ab initio solution. This method has been implemented in a computer package, ACORN, whose main underlying concept is that a proper structural fragment, equivalent to 5-10% of the structure being studied, can give rise to enough information to start a process of Fourier recycling and density modification in real space, leading to the solution of the structure. Tests performed on RNAse AP1 in this thesis and on other structures in another context, have proved that ACORN is a robust procedure and that it can be adapted to many different situations.

Seller Inventory # 9783838372686

Title
Real-Space Methods to Solve Protein Structures : Improved Density-Modification Techniques for Phasing and Phase Extension in Protein Crystallography.
Author
James Foadi
Publisher
LAP LAMBERT Academic Publishing
Publication year
2010
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3838372689
ISBN 13
9783838372686
Item weight
298 grams
Dimensions
220x150x12 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

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