Reduced Order Models for the Biomechanics of Living Organs

Reduced Order Models for the Biomechanics of Living Organs, a new volume in the Biomechanics of Living Organisms series, provides a comprehensive overview of the state-of-the-art in biomechanical computations using reduced order models, along with a deeper understanding of the associated reduction algorithms that will face students, researchers, clinicians and industrial partners in the future. The book gathers perspectives from key opinion scientists who describe and detail their approaches, methodologies and findings. It is the first to synthesize complementary advances in Biomechanical modelling of living organs using reduced order techniques in the design of medical devices and clinical interventions, including surgical procedures.

This book provides an opportunity for students, researchers, clinicians and engineers to study the main topics related to biomechanics and reduced models in a single reference, with this volume summarizing all biomechanical aspects of each living organ in one comprehensive reference.

• Introduces the fundamental aspects of reduced order models
• Presents the main computational studies in the field of solid and fluid biomechanical modeling of living organs
• Explores the use of reduced order models in the fields of biomechanical electrophysiology, tissue growth and prosthetic designs

Francisco Chinesta is currently full Professor of computational physics at Arts et Metiers Institute of Technology (Paris, France) and associated researcher at IMT Mines Albi, Honorary Fellow of the “Institut Universitaire de France” – IUF- and Fellow of the Spanish Royal Academy of Engineering, with major achievements in real-time solution of physics-based models, scientific machine learning, and physics-based and data-driven hybrid models, with more than 500 published papers and many international scientific awards. He received in 2019 the silver medal from the French CNRS and is at present director of the DESCARTES project on Hybrid Artificial Intelligence funded by the NRF at CNRS@CREATE.

Elias Cueto is a Professor of continuum and computational mechanics, Universidad de Zaragoza. His research interests include

the development of numerical methods for computational mechanics in its broadest sense. He has worked on finite element and meshless methods or model order reduction techniques, with applications on forming process simulation, real-time simulation, haptics, computational surgery, and, more recently, on data-intensive computational mechanics and Augmented/Mixed Reality. He has more than 100 articles in leading peer reviewed journals and has worked on 8 books. He is an editor for the International Journal of Material Forming and the ESAFORM book series on Material Forming with Springer. He is on 7 editorial boards for journals.

Yohan Payan is Director of Research at the French National Center for Scientific Research (CNRS). In 1997, he received an award from the University of Grenoble for his doctoral research on the biomechanics of speech production. In 2012, the French Biomechanics Society awarded him the Senior Prize for his research on the biomechanics for computer-assisted surgery. His main research interests concern the biomechanical modeling of soft tissues and their integration into medical devices used to assist surgeons for planning or to guide them during surgery. The corresponding applications concern plastic and maxillofacial surgery, breast cancer treatment, neurosurgery, orthopedics and pressure ulcer prevention, based on organs or musculoskeletal models. He was a Research Affiliate at the Massachusetts Institute of Technology (1999, Boston, USA) and visiting professor at University of Chile (2004, Santiago de Chile) and University of British Columbia (2010, Vancouver, Canada). Yohan Payan is the co-head of the Biomechanics TIMC research team (Univ. Grenoble Alpes) and the Associate Editor of the Clinical Biomechanics journal (Elsevier).

Jacques Ohayon is Professor of Mechanics at the Engineering school Polytech, Univ. Savoie Mont-Blanc, France. From 1985 to 1988, he was visiting fellow at the Biomedical Engineering Branch of the National Institutes of Health (NIH), Bethesda MD, USA. He received the 1998 Junior Prize of the French Biomechanics Society (SB) for his research on the biomechanics of the left ventricle. His current research focuses on the biomechanics of atherosclerotic plaque and the development of new clinical tools for imaging the elasticity of vulnerable plaques. From 2006 to 2007, he was visiting professor at the National Institute of Biomedical Imaging and Bioengineering at the NIH, USA. Jacques Ohayon was the Chairman of the SB, which also awarded him the Senior Prize in 2016 for his work on the biomechanics of coronary plaque rupture. In 2020, he was a visiting professor at Texas A & M University and conducted his research in the field of endothelial cell mechanobiology at the Houston Methodist Research Institute (HMRI). Since 2020, he is also Adjunct Professor of Cardiovascular Sciences at HMRI, Texas, USA.