Reduction: Selectivity, Strategy & Efficiency in Modern Organic Chemistry (Comprehensive Organic Synthesis II - Online) Trost, Barry M.

This volume contains 37 chapters on methods for reducing functional groups, organized into four main parts. (i) Reduction of C=X systems, where X is an electronegative heteroatom, divided into 14 chapters based on the degree of reduction, the oxidation level of the C=X substrate, and on the nature of the reagent. (ii) Reduction of X=Y systems, divided into three chapters, covering the reduction of such groups as nitro, azo, and the various kinds of P=O and S=O groups. (iii) Reduction of C=C and C≡C, divided into 12 chapters based on the method of reduction, with aromatic, heteroaromatic, and conjugated systems treated separately, and including an extensive discussion of hydrometallation. (iv) Reduction of single bonds, C-X to C-H, in eight chapters, including the hydrogenolysis of the various kinds of C-X bonds, the reduction of epoxides, and the reduction of vinyl derivatives to alkenes. Each chapter includes a discussion of chemoselectivity, regioselectivity, and stereoselectivity, wherever it is appropriate, and most include advice on the reagent of choice, and the mechanistic basis of the various methods of reduction. In short, it is, within the space available, as near to a comprehensive account of reduction in organic chemistry as one could hope for.

Essential for all industrial and academic chemistry libraries serving advanced undergraduate and graduate systems. -- H.T. McKone, Saint Joseph College, Choice

January 1993
'I gazed and gazed but little thought, what wealth to me the show had brought'. What daffodils did to Wordsworth, this treatise did to me. Wordsworth saw 10,000 daffodils at a glance. Here I saw nearly 10,000 pages of text and 9000 references, together with an abundance of beautifully drawn structures and reaction schemes; here I shared the enthusiasm of over 250 distinguished chemists from across the globe as they unfurled the art of modern organic synthesis in nine fat volumes. This vast undertaking has been supremely well organised, employing internationally renowned synthetic chemists as editors.... This series presents a refreshing overview of modern synthetic methodology and provokes many tantalising questions and thoughts.... Anyone who synthesises organic compounds must have access to them.
(R.M. Scrowston, Chemistry in Britain)
-- R.M. Scrowston, Chemistry in Britain

October 1992 Essential for all industrial and academic chemistry libraries serving advanced undergraduate and graduate systems. -- H.T. McKone, Saint Joseph College, Choice

October 1992
Essential for all industrial and academic chemistry libraries serving advanced undergraduate and graduate systems.
(H.T. McKone, Saint Joseph College, Choice)
-- H.T. McKone, Saint Joseph College, Choice