Regulation of the RAS Signalling Network

Language: English

Published by Springer Nature B.V., 1996

0412118610 / 9780412118616

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Druck auf Anfrage Neuware - Printed after ordering - Inhaltsangabe1. Genetics of RAS Signaling in Drosophila.- I. Introduction.- II. Background to the Experimental Systems.- III. Protein Tyrosine Kinase Receptors.- IV. Linking RAS with Tyrosine Kinase Receptors.- V. A Kinase Cascade Downstream of RAS.- VI. Nuclear Events.- VII. Concluding Remarks.- 2. RAS-Mediated Signal Transduction in C. elegans.- I. Introduction.- II. Genetic Approaches Used to Study Vulval Signal Transduction.- III. Genetic and Molecular Analysis of the let-60 RAS Gene.- IV. Genes Acting Upstream of RAS.- V. Genes Acting Downstream of RAS.- VI. Multiple Functions of the let-60 RAS-mediated Signal Transduction Pathway During C elegans Development.- 3. Mammals I: Regulation of RAS Activation.- I. Introduction.- II. Growth Factor/Cytokine Signaling.- III. Growth Factor Cascades: Autocrine Stimulation.- 4. Prenylation of RAS and Inhibitors of Prenyltransferases.- I. Introduction.- II. C-Terminal Modification of RAS Proteins.- III. Farnesyltransferase and Geranylgeranyltransferases.- IV. Mutational Analyses of Prenyltransferases.- V. Inhibitors of Prenylation.- VI. Biological Effects of Prenyltransferase Inhibitors.- 5. Mammals II: Downstream of RAS and Actin-Cytoskeleton.- I. RAS GAPs.- II. Oncogenic Mutations of RAS.- III. Effectors of RAS.- IV. Actin-Cytoskeleton.- V. G Proteins in the Rho Family (Rho, Rac and CDC42).- VI. RAS-Activated or -Repressed Genes.- 6. From RAS to MAPK: Cell-Free Assay System for RAS- and Rap 1-Dependent B-Raf Activation.- I. Introduction.- II. Cell-free Assay System for the RAS-dependent Activation of the MAP Kinase Cascade in Xenopus Oocyte Cytosol.- III. REKS.- IV. Raf Activation.- V. Conclusion.…

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Title
Regulation of the RAS Signalling Network
Author
Hiroshi Maruta
Publisher
Springer Nature B.V.
Publication year
1996
Condition
Neu
Binding
Buch
Language
English
ISBN 10
0412118610
ISBN 13
9780412118616
Item weight
596 grams
Dimensions
254x178x14 mm

AHA-BUCH GmbH

Einbeck, Germany

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