Regulatory Mechanisms of Striated Muscle Contraction (Advances in Experimental Medicine and Biology)

Troponin is a central subject in biochemical, biophysical, and physiological research. The discovery of this protein initiated a new era in research into the molecular biology of the regulation of contraction in striated muscle. This volume covers the entire spectrum of research on troponin and related muscle proteins, including pathophysiological and clinical aspects. It details recent advances in work on the genetic disorders of cardiac troponin and ryanodine receptor proteins. Many color figures illustrate the three-dimensional structures of the proteins involved in the muscle functions. The book will help readers understand characteristic features of the regulatory mechanisms of striated muscle contraction and their disorders at the molecular level.

From the reviews:

"This book comprehensively covers the accumulated knowledge of the regulatory mechanisms controlling striated muscle contraction. The organization and presentation of basic research findings ... result in an excellent book that accurately represents the history and current state of the field. ... It is written for practitioners of basic and clinical research in the field of striated muscle function and dysfunction. ... It contains a wealth of information that is organized in an excellent manner, allowing the reader to quickly locate areas of interest and relevance." (Kristin L. Gosselink, Doody’s Review Service, September, 2008)