Reliability and validity of Rhabdomayosarcoma histological diagnosis

Language: English

Published by LAP LAMBERT Academic Publishing, 2019

6202058641 / 9786202058643

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Rhabdomyosarcomas (RMS) are soft tissue tumours of skeletal differentiation that are relatively common. They present a diagnostic challenge in histopathology laboratories where immunohistochemistry (IHC) staining is not routine. They tend to mimic many other tumours morphologically like small round blue cell tumour. Objectives: The aim of this study was to determine the reliability and validity of the morphological diagnosis of rhabdomyosarcoma using haematoxylin and eosin (H & E) with IHC as the reference standard in the Department of Pathology. This was a laboratory-based cross-sectional study to assess the reliability and validity of the morphological diagnosis of haematoxylin and eosin. All cases of rhabdomyosarcoma diagnosed using H&E during the study period from January 2000 to December 2012 in the Department of Pathology were sampled. The sample size in this study was 200 samples. Haematoxylin and eosin method has high sensitivity but low specificity with fairly high diagnostic accuracy. Therefore confirmation of all RMS cases diagnosed by H and E using IHC is necessary, as haematoxylin and eosin method has a high false positive rate.…

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Title
Reliability and validity of Rhabdomayosarcoma histological diagnosis
Author
Eva Mbwilo
Publisher
LAP LAMBERT Academic Publishing
Publication year
2019
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6202058641
ISBN 13
9786202058643
Item weight
96 grams
Dimensions
220x150x4 mm

AHA-BUCH GmbH

Einbeck, Germany

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