Repair and Redesign of Physiological Systems (Design and Nature)

In this volume the authors highlight the role of engineering and relevant
mathematics in medicine. Like engineering systems, human physiology can wear out or fail to an extent where it requires a clinical interventionist to repair or even redesign the system. There is a long tradition among clinicians of working with engineers and mathematicians. This volume continues that theme, with modern developments. Hence chapters deal with vascular surgery planning, cardiac and vascular devices, immunotherapeutics, plus nasal and dental repair. More generically, some of the chapters relate to preserving the integrity of the human `surface structure, as well as the challenges in computer modeling of the complexities and multiscale nature of the human physiome.

Mark ATHERTON (PhD, City University, London; MSc, Imperial College, London; BSc(Hons), Aston University, Birmingham) is a reader in mechanical engineering design at Brunel University. His research interests include the robustness of mechanical/mechatronic devices, natural and complex systems. In the medical field his research focuses on modelling blood flow through vascular stents subject to geometric risk factors; and reducing the unpleasant noise of dental drills using digital filtering and anti-noise techniques. Michael COLLINS,after graduating from Oxford University in Engineering Science, worked in the UK nuclear industry for three years in the field of fuel element heat transfer. He spentover thirty yearsat City University:his research involved computational thermofluids, for which he was awarded both PhD and DSc degrees. His interests broadened into novel optical measurement methods and the application of Computational Fluid Dynamics to medical flow problems.International recognition includes the award of the PolishOrder of Merit and he is an Honorary Fellow of the Italian Union of Thermofluiddynamics.He is currently a Visiting Professor in the School of Engineering and Design at Brunel University, working in advanced industrial applications of CFD, micro & nanofluid dynamics,and medical flow modelling withDr Atherton. He is a Fellow of six engineering, mathematical and other professional group and the Founding Editor of this book Series.