Retinoids: Progress in Research and Clinical Applications

Maria A. Livrea, Lester Packer

ISBN 10: 0824787587 ISBN 13: 9780824787585

Published by Marcel Dekker, Inc., 1993

Language: English

Condition: Used - Very good Hardcover

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Hardcover in excellent condition: slight handling, original owner's name inside the front cover, otherwise unmarked. 648 pages. [2.2 lbs].

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Bibliographic Details

Title

Retinoids: Progress in Research and Clinical Applications

Publisher

Marcel Dekker, Inc.

Publication Date

1993

Language

English

ISBN 10

0824787587

ISBN 13

9780824787585

Binding

Hardcover

Condition

Very Good

Book Type

Book

Seller catalogs

Chemistry/ Biochemistry

About this title

Synopsis

This volume contains papers presented at the Conference on Retinoids: New Trends in Research and Clinical Applications, held in 1991 in Palermo, Italy, describing the latest research findings on biochemistry, nutrition, molecular and cell biology and developmental biology, as well as the pharmacology and the therapeutic use of vitamin A and its congeners.;Written by leading authorities in the field from the USA, Europe and Japan, Retinoids, amongst other things: addresses retinol-supported retinoic acid (RA) synthesis and catabolism; identifies synthetic ligands with a high selective affinity for RAR-alpha, -beta and -gamma nuclear receptors, determining if they would show pharmacological properties similar to the natural parent substance all-trans RA; considers the embryonic/foetal cellular retinoid-binding proteins and evidence for their participation in normal and abnormal morphogenesis; discusses a novel arotinoid, Ro 40-8757, that exhibited improved anti-tumour efficacy and safety in pre-clinical tests; and reports the audioradiographic distribution of retinol and RA in organs of pregnant hamsters and foetuses.

Review

." . .an outstanding book, current in its information, extensive in the contributions from many of the leading researchers, and very well organized and indexed." ---Journal of Optimal Nutrition

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