Role of Adenosine in Regulating Atrial Secretory Response: Decreased Nutrient Flow

Conde, Valney Mara Gomes; L.W.P. Diniz, Domingos

ISBN 10: 6208660084 / ISBN 13: 9786208660086

Published by Our Knowledge Publishing, 2025

About this Item

Seller Inventory # I-9786208660086

Bibliographic Details

• Title: Role of Adenosine in Regulating Atrial Secretory Response: Decreased Nutrient Flow
• Publisher: Our Knowledge Publishing
• Publication Date: 2025
• Language: English
• ISBN 10: 6208660084
• ISBN 13: 9786208660086
• Binding: Soft cover
• Condition: New

About this title

Synopsis

Adenosine exerts potent effects on many physiological processes, including the regulation of cardiac activity, on which it can act as a local homeostatic factor, under normal or altered conditions of variation in its metabolism. The modulation of contractile activity, coronary perfusion and the synthesis and secretion of other local cell protection factors, such as atrial natriuretic peptide (ANP) and nitric oxide (NO), are some of the various effects induced by its external membrane receptors. We set out to evaluate the effects of specific reuptake or degradation blockers, adenosine antagonists and agonists in order to study the functional significance of the effects of interstitial adenosine on ANP secretion, nitric oxide (NO) synthesis and oxygen (O2) consumption in isolated right atria of adult albino rats (WISTAR) subjected to a decrease in perinfusion flow (50%).