IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITION OF FLAVONOIDS | IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITORY ACTIVITY OF SOME SYNTHESIZED FLAVONOID DERIVATIVES

M. Vijayabaskaran (u. a.)

ISBN 10: 6209863264 / ISBN 13: 9786209863264

Published by LAP LAMBERT Academic Publishing, 2026

About this Item

IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITION OF FLAVONOIDS | IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITORY ACTIVITY OF SOME SYNTHESIZED FLAVONOID DERIVATIVES | M. Vijayabaskaran (u. a.) | Taschenbuch | Englisch | 2026 | LAP LAMBERT Academic Publishing | EAN 9786209863264 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.

Seller Inventory # 135420405

Bibliographic Details

• Title: IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITION OF FLAVONOIDS | IN SILICO AND IN VITRO ALDOSE REDUCTASE INHIBITORY ACTIVITY OF SOME SYNTHESIZED FLAVONOID DERIVATIVES
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2026
• Language: English
• ISBN 10: 6209863264
• ISBN 13: 9786209863264
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 220W x 150H x 6D millimeters 220 millimeters width by 150 millimeters height by 6 millimeters depth
• Weight: 161 grams
• Seller catalogs:
  • Bücher

About this title

Synopsis

Cataracts are one of the primary causes of visual impairment in diabetics. Patients with diabetes mellitus are said to be five times more likely to acquire cataracts, particularly if they begin the condition early. Flavonoids are bioactive secondary metabolites of plants that belong to a large family of low molecular weight compounds and have a polyphenolic structure. This comprehensive book explores the therapeutic potential of novel flavonoid derivatives in combating diabetic cataractogenesis. Utilizing a multi-disciplinary approach, the research integrates in silico molecular docking to identify high-affinity aldose reductase inhibitors (ARIs) with traditional chemical synthesis and characterization techniques. The core of the investigation lies in a rigorous in vitro evaluation using isolated goat lenses, demonstrating how these specialized compounds retard lens opacification and mitigate oxidative stress. This book provides a critical scaffold for the development of non-surgical, plant-derived pharmacological interventions for vision preservation.