SNEDDS for improved oral Bioavailability of BCS classII drug-IVIVC

Language: English

Published by LAP LAMBERT Academic Publishing Aug 2013, 2013

3659440485 / 9783659440489

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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermanyBuchWeltWeit Ludwig Meier e.K.

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This item is printed on demand - it takes 3-4 days longer - Neuware -Modern drug discovery technique led to the consistent increase in the number of new pharmacologically active lipophilic compounds that are poorly water soluble. A great challenge facing the pharmaceutical scientist is making these molecules into orally administered medications with sufficient bioavailability. One of the most popular approaches to improve the oral bioavailability of these molecules is the utilization of a lipid based drug delivery system. Development and optimization of formulation is an integral part of manufacturing and marketing of any therapeutic agent which is indeed a time consuming and costly process. Optimization process may require alteration in formulation composition, manufacturing process, equipment and batch sizes. If these types of changes are applied to a formulation, studies in human healthy volunteers may be required to prove that the new formulation is bioequivalent with the old one.IVIVC includes in vivo relevance to in vitro dissolution specifications and can serve as surrogate for in vivo bioavailability and to support biowaivers. This book provides the information about the use of biorelevant media as media an alternative for in vivo studies. 68 pp. Englisch.

Seller Inventory # 9783659440489

Title
SNEDDS for improved oral Bioavailability of BCS classII drug-IVIVC
Author
Raman Sureshkumar
Publisher
LAP LAMBERT Academic Publishing Aug 2013
Publication year
2013
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
3659440485
ISBN 13
9783659440489
Item weight
119 grams
Dimensions
220x150x5 mm

BuchWeltWeit Ludwig Meier e.K.

Bergisch Gladbach, Germany

5-star seller

AbeBooks seller since January 11, 2012

Shipping rates from Germany to U.S.A.

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BuchWeltWeit Ludwig Meier e.K.

Germany