SYSTEMS BIOLOGY Constraint - Based Modeling of Metabolic Networks : In silico Analysis, Modeling and Engineering of Escherichia Coli Metabolic Network for Succinic Acid Production

Language: English

Published by LAP LAMBERT Academic Publishing, 2022

6204750240 / 9786204750248

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Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH

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nach der Bestellung gedruckt Neuware - Printed after ordering - Systems Biology is a powerful tool widely used to analyze in silico complex biological systems and subsystems, to understand the cellular behavior at the system-level; what kind of interactions are between cellular components and how are these networks organized and reorganized under different pressures, such as harsh environmental conditions, culture medium and even genetic modifications. In the present study the applications of constraint-based metabolic models and systems biology in metabolic engineering are discussed. Using these approaches the production potential of succinic acid from renewable resources (glucose or glycerol in minimal media) in Escherichia coli is analyzed. Simulations are made to determine which competitive pathways should be modified to reroute the carbon flux toward succinic acid and to determine the environmental conditions and metabolic engineering effects on cell metabolism. During the experiments different in silico and in vivo methods have been implemented to model, analyze, optimize and predict the metabolic behavior of E. coli.

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Title
SYSTEMS BIOLOGY Constraint - Based Modeling of Metabolic Networks : In silico Analysis, Modeling and Engineering of Escherichia Coli Metabolic Network for Succinic Acid Production
Author
Zsolt Bodor
Publisher
LAP LAMBERT Academic Publishing
Publication year
2022
Condition
Neu
Binding
Taschenbuch
Language
English
ISBN 10
6204750240
ISBN 13
9786204750248
Item weight
298 grams
Dimensions
220x150x12 mm

AHA-BUCH GmbH

Einbeck, Germany

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AbeBooks seller since August 14, 2006

Shipping rates from Germany to U.S.A.

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