Scientific Validation Of Polyherbal Hepatoprotective Formulation | Curing The Liver

Beerendra Kumar Saroj (u. a.)

ISBN 10: 3659250759 ISBN 13: 9783659250750

Published by LAP Lambert Academic Publishing, 2012

Language: English

Condition: New Soft cover

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Bibliographic Details

Title

Scientific Validation Of Polyherbal Hepatoprotective Formulation | Curing The Liver

Publisher

LAP Lambert Academic Publishing

Publication Date

2012

Language

English

ISBN 10

3659250759

ISBN 13

9783659250750

Binding

Taschenbuch

Condition

Neu

Seller catalogs

B�cher

About this title

Synopsis

This polyherbal formulation has been traditionally used in the Indian system of medicine as a chief formulation for the treatment of hepatic diseases as hepatoprotective. The aim of the study was to study hepatoprotective activity which will be scientific validation of traditional knowledge claimed about this polyherbal formulation. Hepatotoxicity was induced by administration of paracetamol (300mg/kg) to the animals. The levels of liver enzymes, lipid profiles, creatinine, urea levels and histopathological parameters were measured in order to evaluate hepatoprotective activity of polyherbal formulation. The polyherbal formulation produced a significant hepatoprotective activity of the decoction of polyherbal formulation. The polyherbal formulation (PHF = 1) shows good hepatoprotective activity by lowering the levels of SGOT, alkaline phosphatase, bilirubin parameters (p<0.05), lipid profiles – cholesterol, triglyceride, LDL and histopathological evaluations shows that PHF = 1 and PHF = 3 formulations have significantly hepatoprotective activity (p<0.05). The study validates that polyherbal formulation has a good hepatoprotective activity.

About the Author

Beerendra Kumar Saroj, M.Pharma.: Studied Pharmacy at Indian Institute of Technology, Banaras Hinhu University (IIT - BHU).

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