The Search for New Anticancer Drugs

M. J. Waring

ISBN 10: 9401066590 / ISBN 13: 9789401066594

Published by Springer, Springer, 2011

About this Item

Druck auf Anfrage Neuware - Printed after ordering - Most of the anti-cancer drugs in use today were discovered by happy accident rather than design, yet the rational design of better anti-cancer drugs remains a cherished goal, and one of the most important challenges facing medical science. This book represents a compilation of views and progress reports which illustrate the diversity of approaches to the problem. Recent research has confirmed the belief that critical genetic changes are at work in cancer cells. The genome, then (DNA in biochemical terms), surely represents a critical target for specific chemotherapy of cancer, and several chapters address the issue of attacking DNA, gene targetting, and the like. Others deal with principles of rational design, exploitation of novel modalities and targets, or the nuts and bolts of antitumour drug testing. While no attempt has been made to provide a comprehensive coverage of this wide-ranging and vitally important subject, the present volume in the series will provide much food for thought.

Seller Inventory # 9789401066594

Bibliographic Details

• Title: The Search for New Anticancer Drugs
• Publisher: Springer, Springer
• Publication Date: 2011
• Language: English
• ISBN 10: 9401066590
• ISBN 13: 9789401066594
• Binding: Taschenbuch
• Condition: Neu
• Dimensions: 235W x 155H x 17D millimeters 235 millimeters width by 155 millimeters height by 17 millimeters depth
• Weight: 452 grams

About this title

Synopsis

Most of the anti-cancer drugs in use today were discovered by happy accident rather than design, yet the rational design of better anti-cancer drugs remains a cherished goal, and one of the most important challenges facing medical science.
This book represents a compilation of views and progress reports which illustrate the diversity of approaches to the problem. Recent research has confirmed the belief that critical genetic changes are at work in cancer cells. The genome, then (DNA in biochemical terms), surely represents a critical target for specific chemotherapy of cancer, and several chapters address the issue of attacking DNA, gene targetting, and the like. Others deal with principles of rational design, exploitation of novel modalities and targets, or the nuts and bolts of antitumour drug testing. While no attempt has been made to provide a comprehensive coverage of this wide-ranging and vitally important subject, the present volume in the series will provide much food for thought.

Review

` Overall, then, a well-edited and pretty up-to-date collection of interesting and useful articles. I would recommend it for a post-graduate seminar or debate on the medicinal chemistry of cancer. '
Annals of Oncology

` This book is recommended both for scientists engaged in anticancer drug development and for the interested outsider. In general it is well produced and, apart from a few exceptions, most of the chemical structures are refreshingly well drawn. The individual chapters are nicely sub-sectioned and all are comprehensively referenced to the primary literature; indeed some of the references have already been useful in our own work. '
Clinical Oncology, 5:4