Selective Estrogen Receptor Modulators : A New Brand of Multitarget Drugs
Language: English
Published by Springer Vieweg, 2014
- Softcover
- New
Seller: AHA-BUCH GmbH, Einbeck, GermanyAHA-BUCH GmbH
AbeBooks seller since August 14, 2006
Condition: New
US$ 179.34
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Add to basketItem description from seller
Druck auf Anfrage Neuware - Printed after ordering - The increasing awareness on the varied consequences of hypogonadism in distinct organs and systems has supported the notion of estrogens as systemic agents. This observation is congruent with the variety of tissues affected by - trogens when used in hormone therapy formulations on hypogonadic women. Apart from the genital tract and the breast, recognized as traditional targets for estrogens, the skeleton, the vascular tree, or the central nervous system, are good examples of territories that have demonstrated sensitivity to estrogens. This evidence has created great interest, as shown by the great amount of lit- ature that has been produced on the bene ts and risks associated with the use of estrogens. In parallel to the clinical interest, basic research has improved our kno- edge on the complexities involved in estrogen action at the molecular level. Together with effects mediated through speci c receptors, a concept that has been the mainstay of the interpretation of estrogen action for years, there is enough evidence to hold the notion of receptor-independent effects. The substantial advances in modern technology applied to research have helped in enlightening the particulars of this versatile action of estrogens. This more detailed knowledge on the sophisticated mechanism of action of estrogens has nourished the emergence of multiple hypotheses speculating with the p- sibility of manipulating estrogen action. The notion that a widely extended regulatory system of cell function, as it is the estrogen receptor machinery, might be modulated at wish has arisen as an attractive, although still elusive postulate.…
Seller Inventory # 9783642445521
- Title
- Selective Estrogen Receptor Modulators : A New Brand of Multitarget Drugs
- Author
- Jose Luis Duenas-Diez
- Publisher
- Springer Vieweg
- Publication year
- 2014
- Condition
- Neu
- Binding
- Taschenbuch
- Language
- English
- ISBN 10
- 3642445527
- ISBN 13
- 9783642445521
- Item weight
- 569 grams
- Dimensions
- 235x155x21 mm
"Synopsis" may belong to another edition of this title.
Review
From the reviews of the first edition:
"Sanchez and colleagues have assembled a timely addition to the clinician’s library. Their book is an up-to-date synthesis of the basic mechanisms of action of estrogen and SERMs with a comprehensive analysis of receptor-mediated and non-receptor mediated events in target tissue. The sections on new SERMs and the clinical endocrinology of SERMs are very useful and will remain so for some time. The choice of basic and clinical topics makes for interesting reading. ... Overall, the book is well written and easy to read." (V. Craig Jordan, The New England Journal of Medicine, January, 2007)
"About the title" may belong to another edition of this title.
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| Item | 5 to 7 business days | 7 to 10 business days |
|---|---|---|
| First item | US$ 35.00 | US$ 35.00 |
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