Selective HPLC Method: Stability indicating Method

Lotfy, Hayam M., M. Abdel-Moety, Ezzat, G. Nouman, Eman

ISBN 10: 3843361215 / ISBN 13: 9783843361217

Published by LAP LAMBERT Academic Publishing, 2012

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Bibliographic Details

• Title: Selective HPLC Method: Stability indicating Method
• Publisher: LAP LAMBERT Academic Publishing
• Publication Date: 2012
• Language: English
• ISBN 10: 3843361215
• ISBN 13: 9783843361217
• Binding: Paperback
• Condition: Like New
• Book Type: book

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Synopsis

Selective HPLC method , Stability indicating high performance liquid chromatographic method ,simultaneous precise determination of promethazine (PROM) and sodium benzoate (SBENZ), even in the presence of the main oxidative degradation products of PROM ,Promethazine (PROM), like other phenothiazines, may become photobiologically active via formation of photolytic products, a number of them being cytotoxic,determination of the comparative protective effect of different antioxidants usually added. Different stability studies were planned to show any interference in the separation of PROM from SBENZ especially in the presence of some common auto-oxidation supressants, such as buylated hydroxy toluene (BHT), buylate hydroxy anisole (BHA) or sodium metabisulfite

About the Author

Asscioate Professor.Hayam Mahmoud Lotfy has obtained her PhD degree in analytical chemistry in 1997, ,Faculty of Pharmacy ,Cairo University ,Egypt. she is author of several articles published in reputed journals in the field of drug analysis ,Pesticide analysis and Pheromone analysis